Appetite for Arginine: Metabolic Control of Macrophage Hunger

Daniel J. Puleston; Erika L. Pearce

doi:10.1016/j.cmet.2020.02.005

Appetite for Arginine: Metabolic Control of Macrophage Hunger

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Engulfment of dying cells by phagocytes is essential to maintain tissue function and promote injury resolution and repair. This process, termed efferocytosis, requires persistent corpse engulfment and remains a poorly understood mechanism. Here, we preview findings from Yurdagul et al. (2020) that detail how continual efferocytosis is supported by metabolites derived from the dying cell itself.

Original language	English (US)
Pages (from-to)	441-442
Number of pages	2
Journal	Cell Metabolism
Volume	31
Issue number	3
DOIs	https://doi.org/10.1016/j.cmet.2020.02.005
State	Published - Mar 3 2020
Externally published	Yes

ASJC Scopus subject areas

Physiology
Molecular Biology
Cell Biology

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10.1016/j.cmet.2020.02.005

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title = "Appetite for Arginine: Metabolic Control of Macrophage Hunger",

abstract = "Engulfment of dying cells by phagocytes is essential to maintain tissue function and promote injury resolution and repair. This process, termed efferocytosis, requires persistent corpse engulfment and remains a poorly understood mechanism. Here, we preview findings from Yurdagul et al. (2020) that detail how continual efferocytosis is supported by metabolites derived from the dying cell itself.",

author = "Puleston, {Daniel J.} and Pearce, {Erika L.}",

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N2 - Engulfment of dying cells by phagocytes is essential to maintain tissue function and promote injury resolution and repair. This process, termed efferocytosis, requires persistent corpse engulfment and remains a poorly understood mechanism. Here, we preview findings from Yurdagul et al. (2020) that detail how continual efferocytosis is supported by metabolites derived from the dying cell itself.

AB - Engulfment of dying cells by phagocytes is essential to maintain tissue function and promote injury resolution and repair. This process, termed efferocytosis, requires persistent corpse engulfment and remains a poorly understood mechanism. Here, we preview findings from Yurdagul et al. (2020) that detail how continual efferocytosis is supported by metabolites derived from the dying cell itself.

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Appetite for Arginine: Metabolic Control of Macrophage Hunger

Abstract

ASJC Scopus subject areas

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