Apparent pseudopuberty in a phenotypic female with a gonadal tumor and an autosome/Y chromosome translocation

I. James Park; Richard H. Heller; Howard W. Jones; J. Donald Woodruff

doi:10.1016/0002-9378(74)90129-X

Apparent pseudopuberty in a phenotypic female with a gonadal tumor and an autosome/Y chromosome translocation

I. James Park, Richard H. Heller, Howard W. Jones, J. Donald Woodruff

School of Medicine

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Abstract

A 15-year-old phenotypic female with a Y/autosome translocation is reported. This patient had a 45,X,-16,+t(16 Yp-) 46,XYq-,-16,+t(16 Yp-) chromosome complement in a lymphocyte culture. Her left gonad showed dysgerminoma and a Sertoli-cell tumor. The right gonad showed gonadoblastoma in a streak and a poorly developed ovary. It was concluded that the pubertal events in this patient came from the estrogens secreted from a Sertoli-cell tumor rather than the function of poorly developed ovary.

Original language	English (US)
Pages (from-to)	661-668
Number of pages	8
Journal	American journal of obstetrics and gynecology
Volume	119
Issue number	5
DOIs	https://doi.org/10.1016/0002-9378(74)90129-X
State	Published - Jul 1 1974

ASJC Scopus subject areas

Obstetrics and Gynecology

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title = "Apparent pseudopuberty in a phenotypic female with a gonadal tumor and an autosome/Y chromosome translocation",

abstract = "A 15-year-old phenotypic female with a Y/autosome translocation is reported. This patient had a 45,X,-16,+t(16 Yp-) 46,XYq-,-16,+t(16 Yp-) chromosome complement in a lymphocyte culture. Her left gonad showed dysgerminoma and a Sertoli-cell tumor. The right gonad showed gonadoblastoma in a streak and a poorly developed ovary. It was concluded that the pubertal events in this patient came from the estrogens secreted from a Sertoli-cell tumor rather than the function of poorly developed ovary.",

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AU - Park, I. James

AU - Heller, Richard H.

AU - Jones, Howard W.

AU - Woodruff, J. Donald

PY - 1974/7/1

Y1 - 1974/7/1

N2 - A 15-year-old phenotypic female with a Y/autosome translocation is reported. This patient had a 45,X,-16,+t(16 Yp-) 46,XYq-,-16,+t(16 Yp-) chromosome complement in a lymphocyte culture. Her left gonad showed dysgerminoma and a Sertoli-cell tumor. The right gonad showed gonadoblastoma in a streak and a poorly developed ovary. It was concluded that the pubertal events in this patient came from the estrogens secreted from a Sertoli-cell tumor rather than the function of poorly developed ovary.

AB - A 15-year-old phenotypic female with a Y/autosome translocation is reported. This patient had a 45,X,-16,+t(16 Yp-) 46,XYq-,-16,+t(16 Yp-) chromosome complement in a lymphocyte culture. Her left gonad showed dysgerminoma and a Sertoli-cell tumor. The right gonad showed gonadoblastoma in a streak and a poorly developed ovary. It was concluded that the pubertal events in this patient came from the estrogens secreted from a Sertoli-cell tumor rather than the function of poorly developed ovary.

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JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

IS - 5

ER -

Apparent pseudopuberty in a phenotypic female with a gonadal tumor and an autosome/Y chromosome translocation

Abstract

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