Apoptosis in cardiac disease - What is it - How does it occur

Michael Neuss, Michael T Crow, Alan Chesley, Edward G. Lakatta

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


This review will present a summary of a description of apoptotic pathways in the heart, followed by ways to measure it and the experimental and clinical evidence for the role of apoptosis in cardiac disease. An evaluation of the effectiveness of pharmacological and other therapeutic interventions in the prevention of apoptosis in the context of cardiac disease will also be presented.

Original languageEnglish (US)
Pages (from-to)507-523
Number of pages17
JournalCardiovascular Drugs and Therapy
Issue number6
StatePublished - 2001
Externally publishedYes


  • Adrenergic receptor
  • Apoptosis
  • Caspase
  • Heart
  • Mitochondria

ASJC Scopus subject areas

  • Pharmacology
  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)


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