Apoptosis in cardiac disease - What is it - How does it occur

Michael Neuss; Michael T Crow; Alan Chesley; Edward G. Lakatta

doi:10.1023/A:1013715704835

Apoptosis in cardiac disease - What is it - How does it occur

Michael Neuss, Michael T Crow, Alan Chesley, Edward G. Lakatta

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

This review will present a summary of a description of apoptotic pathways in the heart, followed by ways to measure it and the experimental and clinical evidence for the role of apoptosis in cardiac disease. An evaluation of the effectiveness of pharmacological and other therapeutic interventions in the prevention of apoptosis in the context of cardiac disease will also be presented.

Original language	English (US)
Pages (from-to)	507-523
Number of pages	17
Journal	Cardiovascular Drugs and Therapy
Volume	15
Issue number	6
DOIs	https://doi.org/10.1023/A:1013715704835
State	Published - 2001
Externally published	Yes

Keywords

Adrenergic receptor
Apoptosis
Caspase
Heart
Mitochondria

ASJC Scopus subject areas

Pharmacology
Cardiology and Cardiovascular Medicine
Pharmacology (medical)

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10.1023/A:1013715704835

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abstract = "This review will present a summary of a description of apoptotic pathways in the heart, followed by ways to measure it and the experimental and clinical evidence for the role of apoptosis in cardiac disease. An evaluation of the effectiveness of pharmacological and other therapeutic interventions in the prevention of apoptosis in the context of cardiac disease will also be presented.",

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AB - This review will present a summary of a description of apoptotic pathways in the heart, followed by ways to measure it and the experimental and clinical evidence for the role of apoptosis in cardiac disease. An evaluation of the effectiveness of pharmacological and other therapeutic interventions in the prevention of apoptosis in the context of cardiac disease will also be presented.

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KW - Caspase

KW - Heart

KW - Mitochondria

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Apoptosis in cardiac disease - What is it - How does it occur

Abstract

Keywords

ASJC Scopus subject areas

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