Apo-E genotype and verbal deficits in Alzheimer's disease

D. Xeno Rasmusson; Gloria Dal Forno; Jason Brandt; Andrew C. Warren; Juan Troncoso; Constantine Lyketsos

doi:10.1176/jnp.8.3.335

Apo-E genotype and verbal deficits in Alzheimer's disease

D. Xeno Rasmusson, Gloria Dal Forno, Jason Brandt, Andrew C. Warren, Juan Troncoso, Constantine Lyketsos

School of Medicine

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Apo-E genotype was not significantly related to cognitive performance in 157 Alzheimer's disease patients. However, patients homozygous for the ε4 allele appeared most impaired on global cognition but least impaired on language measures. Further study with larger samples may reveal that Apo-E genotype accounts for some of the variability in cognitive deficits observed in Alzheimer's disease.

Original language	English (US)
Pages (from-to)	335-337
Number of pages	3
Journal	Journal of Neuropsychiatry and Clinical Neurosciences
Volume	8
Issue number	3
DOIs	https://doi.org/10.1176/jnp.8.3.335
State	Published - 1996

ASJC Scopus subject areas

Clinical Neurology
Psychiatry and Mental health

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title = "Apo-E genotype and verbal deficits in Alzheimer's disease",

abstract = "Apo-E genotype was not significantly related to cognitive performance in 157 Alzheimer's disease patients. However, patients homozygous for the ε4 allele appeared most impaired on global cognition but least impaired on language measures. Further study with larger samples may reveal that Apo-E genotype accounts for some of the variability in cognitive deficits observed in Alzheimer's disease.",

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AU - Troncoso, Juan

AU - Lyketsos, Constantine

PY - 1996

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AB - Apo-E genotype was not significantly related to cognitive performance in 157 Alzheimer's disease patients. However, patients homozygous for the ε4 allele appeared most impaired on global cognition but least impaired on language measures. Further study with larger samples may reveal that Apo-E genotype accounts for some of the variability in cognitive deficits observed in Alzheimer's disease.

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Apo-E genotype and verbal deficits in Alzheimer's disease

Abstract

ASJC Scopus subject areas

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