Aortic valve replacement for the patient with Osler-Rendu-Weber disease

Yoshimasa Seike, H. Sato, M. Nagashima, T. Hori, H. Ishitoya, Narutoshi Hibino, T. Tomino, T. Nakata

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Osler Rendu-Weber (O-R W) disease (hereditary haemorrhagic telangiectasia) is characterized by an anormality of the peripheral blood vessels which often causes recurrent epistaxis. We presented a case of aortic valve replacement for the patient with O-R-W disease. A 75-year-old woman diagnosed as O-R-W disease with chest pain and dyspnea was admitted. Preoperative transthoratic echocardiography showed severe aortic valve stenosis (AS) with a pressure gradient (from left ventricle to ascending aorta) of 72.5 mmHg. Urgent aortic valve replacement (AVR) was performed after preoperative hormonal (estrogen-progesterone) therapy, that might be effective for bleeding from vascular ectasia. No hemorrhagic tendency was recognized and the postoperative course was uneventful.

Original languageEnglish (US)
Pages (from-to)1141-1144
Number of pages4
JournalKyobu geka. The Japanese journal of thoracic surgery
Issue number13
StatePublished - 2005
Externally publishedYes


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