Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp

Joaquim Roca, Ryoji Ishida, James M. Berger, Toshiwo Andoh, James C. Wang

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318 Scopus citations

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Medicine and Dentistry

Biochemistry, Genetics and Molecular Biology

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