Antiretroviral therapy in the experienced patient.

A number of important studies at the 6th Conference on Retroviruses and Opportunistic Infections addressed using antiretroviral therapy in treatment-experienced patients. The growing availability of resistance assays and the expanding list of antiretroviral drugs make therapy both more complex and more effective. Results are presented from studies with nucleoside-experienced patients and protease inhibitor-experienced patients. The role of intensification is discussed and three definitions of that approach are explained. The use of resistance testing in guiding and modifying therapy is also discussed.