Antigenic composition of human renal vascular endothelium assessed by kidney perfusion

W. M. Baldwin; F. H J Claas; J. J. Van Rood; L. A. Van Es

Antigenic composition of human renal vascular endothelium assessed by kidney perfusion

W. M. Baldwin, F. H J Claas, J. J. Van Rood, L. A. Van Es

Research output: Contribution to journal › Article › peer-review

Abstract

Intravascular perfusion of healthy, viable human kidneys either with human sera or with monoclonal antibodies specific for individual HL. A-A, B, DR or E-M antigens demonstrated that all of these antigens are exposed to circulating antibodies and thus can serve as stimuli or targets for immunologic mediators of renal transplant rejection. In addition, these antibodies could be recovered from the renal vessels by brief treatment with acid buffer.

Original language	English (US)
Pages (from-to)	256-262
Number of pages	7
Journal	Tissue Antigens
Volume	23
Issue number	5
State	Published - 1984
Externally published	Yes

ASJC Scopus subject areas

Cell Biology
Immunology

Cite this

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title = "Antigenic composition of human renal vascular endothelium assessed by kidney perfusion",

abstract = "Intravascular perfusion of healthy, viable human kidneys either with human sera or with monoclonal antibodies specific for individual HL. A-A, B, DR or E-M antigens demonstrated that all of these antigens are exposed to circulating antibodies and thus can serve as stimuli or targets for immunologic mediators of renal transplant rejection. In addition, these antibodies could be recovered from the renal vessels by brief treatment with acid buffer.",

author = "Baldwin, {W. M.} and Claas, {F. H J} and {Van Rood}, {J. J.} and {Van Es}, {L. A.}",

year = "1984",

language = "English (US)",

volume = "23",

pages = "256--262",

journal = "HLA",

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publisher = "Wiley-Blackwell",

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AU - Baldwin, W. M.

AU - Claas, F. H J

AU - Van Rood, J. J.

AU - Van Es, L. A.

PY - 1984

Y1 - 1984

N2 - Intravascular perfusion of healthy, viable human kidneys either with human sera or with monoclonal antibodies specific for individual HL. A-A, B, DR or E-M antigens demonstrated that all of these antigens are exposed to circulating antibodies and thus can serve as stimuli or targets for immunologic mediators of renal transplant rejection. In addition, these antibodies could be recovered from the renal vessels by brief treatment with acid buffer.

AB - Intravascular perfusion of healthy, viable human kidneys either with human sera or with monoclonal antibodies specific for individual HL. A-A, B, DR or E-M antigens demonstrated that all of these antigens are exposed to circulating antibodies and thus can serve as stimuli or targets for immunologic mediators of renal transplant rejection. In addition, these antibodies could be recovered from the renal vessels by brief treatment with acid buffer.

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M3 - Article

C2 - 6379984

AN - SCOPUS:0021259453

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Antigenic composition of human renal vascular endothelium assessed by kidney perfusion

Abstract

ASJC Scopus subject areas

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