Anticoagulants and the elderly: A researh dilemma

Jeffrey E. Escher; Steven R. Gambert; Edmund H. Duthie

doi:10.1007/BF02432273

Anticoagulants and the elderly: A researh dilemma

Jeffrey E. Escher, Steven R. Gambert, Edmund H. Duthie

School of Medicine

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Venous thromboembolism is a problem commonly encountered in adult patients. Despite the widely accepted belief that anticoagulants form the basis of therapy, much debate remains regarding their use in the elderly. Although deep venous thrombi and pulmonary emboli are largely age-prevalent disorders, most studies have not addressed the question of whether aging may influence both the metabolic handling of and therapeutic response to anticoagulants. Variability of response as a function of age, as well as attendant risks of anticoagulant therapy in the geriatric patient are discussed. Fertile areas for future research are also summarized.

Original language	English (US)
Pages (from-to)	85-90
Number of pages	6
Journal	AGE
Volume	9
Issue number	3
DOIs	https://doi.org/10.1007/BF02432273
State	Published - Jul 1 1986

ASJC Scopus subject areas

Aging
Geriatrics and Gerontology

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abstract = "Venous thromboembolism is a problem commonly encountered in adult patients. Despite the widely accepted belief that anticoagulants form the basis of therapy, much debate remains regarding their use in the elderly. Although deep venous thrombi and pulmonary emboli are largely age-prevalent disorders, most studies have not addressed the question of whether aging may influence both the metabolic handling of and therapeutic response to anticoagulants. Variability of response as a function of age, as well as attendant risks of anticoagulant therapy in the geriatric patient are discussed. Fertile areas for future research are also summarized.",

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N2 - Venous thromboembolism is a problem commonly encountered in adult patients. Despite the widely accepted belief that anticoagulants form the basis of therapy, much debate remains regarding their use in the elderly. Although deep venous thrombi and pulmonary emboli are largely age-prevalent disorders, most studies have not addressed the question of whether aging may influence both the metabolic handling of and therapeutic response to anticoagulants. Variability of response as a function of age, as well as attendant risks of anticoagulant therapy in the geriatric patient are discussed. Fertile areas for future research are also summarized.

AB - Venous thromboembolism is a problem commonly encountered in adult patients. Despite the widely accepted belief that anticoagulants form the basis of therapy, much debate remains regarding their use in the elderly. Although deep venous thrombi and pulmonary emboli are largely age-prevalent disorders, most studies have not addressed the question of whether aging may influence both the metabolic handling of and therapeutic response to anticoagulants. Variability of response as a function of age, as well as attendant risks of anticoagulant therapy in the geriatric patient are discussed. Fertile areas for future research are also summarized.

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Anticoagulants and the elderly: A researh dilemma

Abstract

ASJC Scopus subject areas

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