Anticoagulants and the elderly: A researh dilemma

Jeffrey E. Escher, Steven R. Gambert, Edmund H. Duthie

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Venous thromboembolism is a problem commonly encountered in adult patients. Despite the widely accepted belief that anticoagulants form the basis of therapy, much debate remains regarding their use in the elderly. Although deep venous thrombi and pulmonary emboli are largely age-prevalent disorders, most studies have not addressed the question of whether aging may influence both the metabolic handling of and therapeutic response to anticoagulants. Variability of response as a function of age, as well as attendant risks of anticoagulant therapy in the geriatric patient are discussed. Fertile areas for future research are also summarized.

Original languageEnglish (US)
Pages (from-to)85-90
Number of pages6
Issue number3
StatePublished - Jul 1 1986

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology


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