Antibiotic sensitivity and resistance patterns in pediatric staphylococcal scalded skin syndrome

Inbal Braunstein; Karolyn A. Wanat; Katrina Abuabara; Karin L. McGowan; Albert C. Yan; James R. Treat

doi:10.1111/pde.12195

Antibiotic sensitivity and resistance patterns in pediatric staphylococcal scalded skin syndrome

Inbal Braunstein, Karolyn A. Wanat, Katrina Abuabara, Karin L. McGowan, Albert C. Yan, James R. Treat

School of Medicine

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Historical resistance patterns often guide empiric antibiotic choices in staphylococcal scalded skin syndrome (SSSS), but little is known about the difference in susceptibility between SSSS and other childhood staphylococcal infections. A retrospective chart review of culture-confirmed cases of SSSS seen in the inpatient dermatology consultation service at the Children's Hospital of Philadelphia between 2005 and 2011 was performed. Most cases of SSSS at our institution are due to oxacillin-susceptible Staphylococcus aureus, and approximately half of the cases are due to clindamycin-resistant strains. Clindamycin and a penicillinase-resistant penicillin are suggested as empiric treatment for SSSS until culture susceptibility data are available to guide therapy.

Original language	English (US)
Pages (from-to)	305-308
Number of pages	4
Journal	Pediatric Dermatology
Volume	31
Issue number	3
DOIs	https://doi.org/10.1111/pde.12195
State	Published - 2014

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Dermatology

Access to Document

10.1111/pde.12195

Cite this

@article{3aab6114f96a408891881726a58bf53b,

title = "Antibiotic sensitivity and resistance patterns in pediatric staphylococcal scalded skin syndrome",

abstract = "Historical resistance patterns often guide empiric antibiotic choices in staphylococcal scalded skin syndrome (SSSS), but little is known about the difference in susceptibility between SSSS and other childhood staphylococcal infections. A retrospective chart review of culture-confirmed cases of SSSS seen in the inpatient dermatology consultation service at the Children's Hospital of Philadelphia between 2005 and 2011 was performed. Most cases of SSSS at our institution are due to oxacillin-susceptible Staphylococcus aureus, and approximately half of the cases are due to clindamycin-resistant strains. Clindamycin and a penicillinase-resistant penicillin are suggested as empiric treatment for SSSS until culture susceptibility data are available to guide therapy.",

author = "Inbal Braunstein and Wanat, {Karolyn A.} and Katrina Abuabara and McGowan, {Karin L.} and Yan, {Albert C.} and Treat, {James R.}",

year = "2014",

doi = "10.1111/pde.12195",

language = "English (US)",

volume = "31",

pages = "305--308",

journal = "Pediatric Dermatology",

issn = "0736-8046",

publisher = "Wiley-Blackwell",

number = "3",

}

TY - JOUR

T1 - Antibiotic sensitivity and resistance patterns in pediatric staphylococcal scalded skin syndrome

AU - Braunstein, Inbal

AU - Wanat, Karolyn A.

AU - Abuabara, Katrina

AU - McGowan, Karin L.

AU - Yan, Albert C.

AU - Treat, James R.

PY - 2014

Y1 - 2014

N2 - Historical resistance patterns often guide empiric antibiotic choices in staphylococcal scalded skin syndrome (SSSS), but little is known about the difference in susceptibility between SSSS and other childhood staphylococcal infections. A retrospective chart review of culture-confirmed cases of SSSS seen in the inpatient dermatology consultation service at the Children's Hospital of Philadelphia between 2005 and 2011 was performed. Most cases of SSSS at our institution are due to oxacillin-susceptible Staphylococcus aureus, and approximately half of the cases are due to clindamycin-resistant strains. Clindamycin and a penicillinase-resistant penicillin are suggested as empiric treatment for SSSS until culture susceptibility data are available to guide therapy.

AB - Historical resistance patterns often guide empiric antibiotic choices in staphylococcal scalded skin syndrome (SSSS), but little is known about the difference in susceptibility between SSSS and other childhood staphylococcal infections. A retrospective chart review of culture-confirmed cases of SSSS seen in the inpatient dermatology consultation service at the Children's Hospital of Philadelphia between 2005 and 2011 was performed. Most cases of SSSS at our institution are due to oxacillin-susceptible Staphylococcus aureus, and approximately half of the cases are due to clindamycin-resistant strains. Clindamycin and a penicillinase-resistant penicillin are suggested as empiric treatment for SSSS until culture susceptibility data are available to guide therapy.

UR - http://www.scopus.com/inward/record.url?scp=84899503143&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84899503143&partnerID=8YFLogxK

U2 - 10.1111/pde.12195

DO - 10.1111/pde.12195

M3 - Article

C2 - 24033633

AN - SCOPUS:84899503143

SN - 0736-8046

VL - 31

SP - 305

EP - 308

JO - Pediatric Dermatology

JF - Pediatric Dermatology

IS - 3

ER -

Antibiotic sensitivity and resistance patterns in pediatric staphylococcal scalded skin syndrome

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this