Abstract
OBJECTIVE: Here we review the literature describing the efficacy and safety of 9 anti-epileptic drugs (AEDs) as migraine prophylaxis. Two of these agents are FDA-approved for this indication. SUMMARY: Several AEDs have demonstrated efficacy in migraine prophylaxis, including divalproex sodium, topiramate and, possibly, gabapentin. Many show encouraging results-even if not definitive. Future clinical trials may provide more evidence for using the newer AEDs in the prophylaxis of migraine.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 18-36 |
| Number of pages | 19 |
| Journal | Headache and Pain: Diagnostic Challenges, Current Therapy |
| Volume | 16 |
| Issue number | 1 |
| State | Published - Dec 7 2005 |
Keywords
- Antiepileptic drugs
- Carbamazepine
- Divalproex sodium
- Gabapentin
- Lamotrigine
- Levetiracetam
- Migraine prophylaxis
- Oxcarbazepine
- Tiagabine
- Topiramate
- Zonisamide
ASJC Scopus subject areas
- Clinical Neurology