Anti-β-endorphin immunoglobulin G in humans

B. F. Roy; J. W. Rose; H. F. McFarland; D. E. McFarlin; D. L. Murphy

doi:10.1073/pnas.83.22.8739

Anti-β-endorphin immunoglobulin G in humans

B. F. Roy, J. W. Rose, H. F. McFarland, D. E. McFarlin, D. L. Murphy

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Human IgG specific for β-endorphin was identified by enzyme-linked immunoabsorbent assay and isolated by affinity chromatography. From a sample of 27 subjects, three individuals with major depression demonstrated plasma IgG highly reactive with human β-endorphin, while four other subjects (two with depression and two randomly selected blood donors) had intermediate reactivity. The recognition site for β-endorphin was retained by F(ab')₂ fragments.

Original language	English (US)
Pages (from-to)	8739-8743
Number of pages	5
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	83
Issue number	22
DOIs	https://doi.org/10.1073/pnas.83.22.8739
State	Published - 1986
Externally published	Yes

ASJC Scopus subject areas

Genetics
General

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abstract = "Human IgG specific for β-endorphin was identified by enzyme-linked immunoabsorbent assay and isolated by affinity chromatography. From a sample of 27 subjects, three individuals with major depression demonstrated plasma IgG highly reactive with human β-endorphin, while four other subjects (two with depression and two randomly selected blood donors) had intermediate reactivity. The recognition site for β-endorphin was retained by F(ab')2 fragments.",

author = "Roy, {B. F.} and Rose, {J. W.} and McFarland, {H. F.} and McFarlin, {D. E.} and Murphy, {D. L.}",

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AU - Roy, B. F.

AU - Rose, J. W.

AU - McFarland, H. F.

AU - McFarlin, D. E.

AU - Murphy, D. L.

PY - 1986

Y1 - 1986

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AB - Human IgG specific for β-endorphin was identified by enzyme-linked immunoabsorbent assay and isolated by affinity chromatography. From a sample of 27 subjects, three individuals with major depression demonstrated plasma IgG highly reactive with human β-endorphin, while four other subjects (two with depression and two randomly selected blood donors) had intermediate reactivity. The recognition site for β-endorphin was retained by F(ab')2 fragments.

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Anti-β-endorphin immunoglobulin G in humans

Abstract

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