TY - JOUR
T1 - Anthropometric growth and utilization of enteral feeding support in pediatric heart transplant recipients
AU - Bannister, Louise
AU - Manlhiot, Cedric
AU - Pollock-Barziv, Stacey
AU - Stone, Tanya
AU - McCrindle, Brian W.
AU - Dipchand, Anne I.
PY - 2010/11/1
Y1 - 2010/11/1
N2 - Bannister L, Manlhiot C, Pollock-BarZiv S, Stone T, McCrindle BW, Dipchand AI. Anthropometric growth and utilization of enteral feeding support in pediatric heart transplant recipients. Pediatr Transplantation 2010: 14:879-886. 2010 John Wiley & Sons A/S. Abstract: We sought to outline trends in anthropometric growth before and after cardiac transplantation and to document our experience with the use of EFS in this population. A total of 130 patients (59% male) were enrolled and followed for a median of 4.4 yr after transplantation. Negative changes over time in weight z-score (EST: -0.256 [0.160] z/yr, p = 0.01), height z-score (EST: -0.214 [0.096] z/yr, p = 0.03), and BMI z-score (EST: -0.287 [0.161] z/yr, p = 0.07) were observed prior to transplantation. Significant increases in weight z-score (EST: +0.342 [0.143] z/yr, p < 0.001) and BMI z-score (EST: +0.396 [0.140] z/yr, p = 0.005) were seen in the first 18 months following transplantation. No further increases in height, weight, or BMI z-score were seen beyond this. Forty-two (32%) patients received EFS. Prior to transplantation, it was not found to be associated with change in anthropomorphic growth. Post-transplantation exposure to EFS was associated with a faster increase in weight z-score (EST: +0.480 [0.231] z/yr, p = 0.04) and height z-score over time (EST: +0.366 [0.141] z/yr, p = 0.01). Normalization of weight and height z-scores was not achieved during the study follow-up period. This study suggests that further investigation into the role of EFS is warranted to identify strategies to improve growth in pediatric heart transplant recipients.
AB - Bannister L, Manlhiot C, Pollock-BarZiv S, Stone T, McCrindle BW, Dipchand AI. Anthropometric growth and utilization of enteral feeding support in pediatric heart transplant recipients. Pediatr Transplantation 2010: 14:879-886. 2010 John Wiley & Sons A/S. Abstract: We sought to outline trends in anthropometric growth before and after cardiac transplantation and to document our experience with the use of EFS in this population. A total of 130 patients (59% male) were enrolled and followed for a median of 4.4 yr after transplantation. Negative changes over time in weight z-score (EST: -0.256 [0.160] z/yr, p = 0.01), height z-score (EST: -0.214 [0.096] z/yr, p = 0.03), and BMI z-score (EST: -0.287 [0.161] z/yr, p = 0.07) were observed prior to transplantation. Significant increases in weight z-score (EST: +0.342 [0.143] z/yr, p < 0.001) and BMI z-score (EST: +0.396 [0.140] z/yr, p = 0.005) were seen in the first 18 months following transplantation. No further increases in height, weight, or BMI z-score were seen beyond this. Forty-two (32%) patients received EFS. Prior to transplantation, it was not found to be associated with change in anthropomorphic growth. Post-transplantation exposure to EFS was associated with a faster increase in weight z-score (EST: +0.480 [0.231] z/yr, p = 0.04) and height z-score over time (EST: +0.366 [0.141] z/yr, p = 0.01). Normalization of weight and height z-scores was not achieved during the study follow-up period. This study suggests that further investigation into the role of EFS is warranted to identify strategies to improve growth in pediatric heart transplant recipients.
KW - anthropometric growth
KW - enteral feeding
KW - heart transplantation
KW - pediatric
UR - http://www.scopus.com/inward/record.url?scp=78349257427&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78349257427&partnerID=8YFLogxK
U2 - 10.1111/j.1399-3046.2010.01361.x
DO - 10.1111/j.1399-3046.2010.01361.x
M3 - Article
C2 - 20667032
AN - SCOPUS:78349257427
SN - 1397-3142
VL - 14
SP - 879
EP - 886
JO - Pediatric Transplantation
JF - Pediatric Transplantation
IS - 7
ER -