Anterior Corneal Disease of Epidermolysis Bullosa Simplex

Anthony P. Adamis; Oliver D. Schein; Kenneth R. Kenyon

doi:10.1001/archopht.1993.01090040091039

Anterior Corneal Disease of Epidermolysis Bullosa Simplex

Anthony P. Adamis, Oliver D. Schein, Kenneth R. Kenyon

School of Medicine

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13 Scopus citations

Abstract

We report the histopathological findings of the anterior cornea from a patient with skin biopsy-proven epidermolysis bullosa simplex. As seen with light microscopy, the cornea had a fibrocellular pannus deep to a thickened epithelial basement membrane. Transmission electron microscopy of the anterior cornea demonstrated a nonhomogeneous basal epithelial layer with abnormal attachment complexes to an irregular, multilaminar basement membrane. The findings of transmission electron microscopy of the bulbar conjunctiva were normal.

Original language	English (US)
Pages (from-to)	499-502
Number of pages	4
Journal	Archives of ophthalmology
Volume	111
Issue number	4
DOIs	https://doi.org/10.1001/archopht.1993.01090040091039
State	Published - Apr 1993

ASJC Scopus subject areas

Ophthalmology

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10.1001/archopht.1993.01090040091039

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title = "Anterior Corneal Disease of Epidermolysis Bullosa Simplex",

abstract = "We report the histopathological findings of the anterior cornea from a patient with skin biopsy-proven epidermolysis bullosa simplex. As seen with light microscopy, the cornea had a fibrocellular pannus deep to a thickened epithelial basement membrane. Transmission electron microscopy of the anterior cornea demonstrated a nonhomogeneous basal epithelial layer with abnormal attachment complexes to an irregular, multilaminar basement membrane. The findings of transmission electron microscopy of the bulbar conjunctiva were normal.",

author = "Adamis, {Anthony P.} and Schein, {Oliver D.} and Kenyon, {Kenneth R.}",

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AU - Schein, Oliver D.

AU - Kenyon, Kenneth R.

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AB - We report the histopathological findings of the anterior cornea from a patient with skin biopsy-proven epidermolysis bullosa simplex. As seen with light microscopy, the cornea had a fibrocellular pannus deep to a thickened epithelial basement membrane. Transmission electron microscopy of the anterior cornea demonstrated a nonhomogeneous basal epithelial layer with abnormal attachment complexes to an irregular, multilaminar basement membrane. The findings of transmission electron microscopy of the bulbar conjunctiva were normal.

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Anterior Corneal Disease of Epidermolysis Bullosa Simplex

Abstract

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