Another burst of smoke: Atomic resolution structures of RF3 bound to the ribosome

Megan E. Mcdonald; Rachel Green

doi:10.1261/rna.032011.111

Another burst of smoke: Atomic resolution structures of RF3 bound to the ribosome

Megan E. Mcdonald, Rachel Green

Howard Hughes Medical Institution

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Two recent reports provide atomic resolution information detailing the interaction of the class II release factor, RF3, with the bacterial ribosome. Differences in the composition of the two crystal forms allow us to learn a considerable amount about how translational GTPases engage the ribosome to facilitate and define conformational rearrangements involved in protein synthesis. Published by Cold Spring Harbor Laboratory Press.

Original language	English (US)
Pages (from-to)	605-609
Number of pages	5
Journal	RNA
Volume	18
Issue number	4
DOIs	https://doi.org/10.1261/rna.032011.111
State	Published - Apr 2012

Keywords

GTPase
RF3
Ribosome
Switch loop
Termination
Translation

ASJC Scopus subject areas

Molecular Biology

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10.1261/rna.032011.111

Cite this

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abstract = "Two recent reports provide atomic resolution information detailing the interaction of the class II release factor, RF3, with the bacterial ribosome. Differences in the composition of the two crystal forms allow us to learn a considerable amount about how translational GTPases engage the ribosome to facilitate and define conformational rearrangements involved in protein synthesis. Published by Cold Spring Harbor Laboratory Press.",

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AB - Two recent reports provide atomic resolution information detailing the interaction of the class II release factor, RF3, with the bacterial ribosome. Differences in the composition of the two crystal forms allow us to learn a considerable amount about how translational GTPases engage the ribosome to facilitate and define conformational rearrangements involved in protein synthesis. Published by Cold Spring Harbor Laboratory Press.

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KW - Ribosome

KW - Switch loop

KW - Termination

KW - Translation

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Another burst of smoke: Atomic resolution structures of RF3 bound to the ribosome

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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