Anatomical Differences Between Human and Pig Hearts and Their Relevance for Cardiac Xenotransplantation Surgical Technique

Aakash Shah, Corbin E. Goerlich, Chetan Pasrija, Jeffrey Hirsch, Stacy Fisher, Patrick Odonkor, Erik Strauss, David Ayares, Muhammad M. Mohiuddin, Bartley P. Griffith

Research output: Contribution to journalArticlepeer-review

Abstract

Cardiac xenotransplantation has been proposed to bridge the gap between supply and demand for patients with end-stage heart failure requiring transplantation. However, differences in pig anatomy compared with human anatomy require modification of the surgical approach. In addition, careful consideration should be given to size matching before transplantation. (Level of Difficulty: Advanced.)

Original languageEnglish (US)
JournalJACC: Case Reports
Volume4
Issue number16
DOIs
StatePublished - Aug 17 2022
Externally publishedYes

Keywords

  • cardiac transplantation
  • chronic heart failure
  • genetic engineering

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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