TY - JOUR
T1 - Anaplastic pseudothyroiditis
AU - Basaria, Shehzad
AU - Udelsman, Robert
AU - Tejedor-Sojo, Javier
AU - Westra, William H.
AU - Krasner, Alan S.
PY - 2002
Y1 - 2002
N2 - Anaplastic thyroid carcinoma (ATC) is one of the most aggressive solid tumours. It generally presents as a rapidly enlarging thyroid mass and produces local symptoms associated with mass effect. One of the very rare presentations of ATC is thyrotoxicosis. We report a patient with ATC whose course was complicated by severe thyrotoxicosis. His symptoms were controlled with beta-blockers. Two weeks into hospitalization, the patient became hypothyroid. Histopathology showed destruction of the normal thyroid follicles by the invasion of the tumour. As this form of thyrotoxicosis resembles various thyroiditides, we hereby refer this condition as 'anaplastic pseudothyroiditis'.
AB - Anaplastic thyroid carcinoma (ATC) is one of the most aggressive solid tumours. It generally presents as a rapidly enlarging thyroid mass and produces local symptoms associated with mass effect. One of the very rare presentations of ATC is thyrotoxicosis. We report a patient with ATC whose course was complicated by severe thyrotoxicosis. His symptoms were controlled with beta-blockers. Two weeks into hospitalization, the patient became hypothyroid. Histopathology showed destruction of the normal thyroid follicles by the invasion of the tumour. As this form of thyrotoxicosis resembles various thyroiditides, we hereby refer this condition as 'anaplastic pseudothyroiditis'.
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U2 - 10.1046/j.1365-2265.2002.01495.x
DO - 10.1046/j.1365-2265.2002.01495.x
M3 - Article
C2 - 11966749
AN - SCOPUS:0036224679
SN - 0300-0664
VL - 56
SP - 553
EP - 555
JO - Clinical Endocrinology
JF - Clinical Endocrinology
IS - 4
ER -