Anaphylaxis to insect stings

David B.K. Golden

doi:10.1016/j.iac.2015.01.007

Anaphylaxis to insect stings

David B.K. Golden

Johns Hopkins Bayview Hospital

Research output: Contribution to journal › Review article › peer-review

40 Scopus citations

Abstract

Anaphylaxis to insect stings has occurred in 3% of adults and can be fatal even on the first reaction. Large local reactions are more frequent but rarely dangerous. The chance of a systemic reaction to a sting is 5% to 10% in large local reactors and in children with mild (cutaneous) systemic reactions, and varies between 30% and 65% in adults with previous systemic reactions, depending on the severity of previous sting reactions. Baseline serum tryptase level is increased in many patients with sting anaphylaxis. Venom immunotherapy is 75% to 98% effective in preventing sting anaphylaxis.

Original language	English (US)
Pages (from-to)	287-302
Number of pages	16
Journal	Immunology and Allergy Clinics of North America
Volume	35
Issue number	2
DOIs	https://doi.org/10.1016/j.iac.2015.01.007
State	Published - May 1 2015

Keywords

Anaphylaxis
Diagnostic tests
Hymenoptera
Immunotherapy
Insect sting
Mastocytosis
Venom

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1016/j.iac.2015.01.007

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title = "Anaphylaxis to insect stings",

abstract = "Anaphylaxis to insect stings has occurred in 3% of adults and can be fatal even on the first reaction. Large local reactions are more frequent but rarely dangerous. The chance of a systemic reaction to a sting is 5% to 10% in large local reactors and in children with mild (cutaneous) systemic reactions, and varies between 30% and 65% in adults with previous systemic reactions, depending on the severity of previous sting reactions. Baseline serum tryptase level is increased in many patients with sting anaphylaxis. Venom immunotherapy is 75% to 98% effective in preventing sting anaphylaxis.",

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AB - Anaphylaxis to insect stings has occurred in 3% of adults and can be fatal even on the first reaction. Large local reactions are more frequent but rarely dangerous. The chance of a systemic reaction to a sting is 5% to 10% in large local reactors and in children with mild (cutaneous) systemic reactions, and varies between 30% and 65% in adults with previous systemic reactions, depending on the severity of previous sting reactions. Baseline serum tryptase level is increased in many patients with sting anaphylaxis. Venom immunotherapy is 75% to 98% effective in preventing sting anaphylaxis.

KW - Anaphylaxis

KW - Diagnostic tests

KW - Hymenoptera

KW - Immunotherapy

KW - Insect sting

KW - Mastocytosis

KW - Venom

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Anaphylaxis to insect stings

Abstract

Keywords

ASJC Scopus subject areas

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