Anaphylaxis to insect stings

David B.K. Golden

Research output: Contribution to journalReview articlepeer-review

40 Scopus citations


Anaphylaxis to insect stings has occurred in 3% of adults and can be fatal even on the first reaction. Large local reactions are more frequent but rarely dangerous. The chance of a systemic reaction to a sting is 5% to 10% in large local reactors and in children with mild (cutaneous) systemic reactions, and varies between 30% and 65% in adults with previous systemic reactions, depending on the severity of previous sting reactions. Baseline serum tryptase level is increased in many patients with sting anaphylaxis. Venom immunotherapy is 75% to 98% effective in preventing sting anaphylaxis.

Original languageEnglish (US)
Pages (from-to)287-302
Number of pages16
JournalImmunology and Allergy Clinics of North America
Issue number2
StatePublished - May 1 2015


  • Anaphylaxis
  • Diagnostic tests
  • Hymenoptera
  • Immunotherapy
  • Insect sting
  • Mastocytosis
  • Venom

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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