Analgesic therapy for major spine surgery

Varun Puvanesarajah, Jason A. Liauw, Sheng Fu Lo, Ioan A. Lina, Timothy F. Witham, Allan Gottschalk

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Pain following spine surgery is often difficult to control and can persist. Reduction of this pain requires a multidisciplinary approach that depends on contributions of both surgeons and anesthesiologists. The spine surgeon’s role involves limiting manipulation of structures contributing to pain sensation in the spine, which requires an in-depth understanding of the specific anatomic etiologies of pain originating along the spinal axis. Anesthesiologists, on the other hand, must focus on preemptive, multimodal analgesic treatment regimens. In this review, we first discuss anatomic sources of pain within the spine, before delving into a specific literature-supported pain management protocol intended for use with spinal surgery.

Original languageEnglish (US)
Pages (from-to)407-419
Number of pages13
JournalNeurosurgical Review
Issue number3
StatePublished - Jul 18 2015


  • Acute pain
  • Analgesia
  • Anesthesia
  • Chronic pain
  • FBSS
  • Failed back surgery syndrome
  • Spine surgery

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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