TY - JOUR
T1 - An update on publicly funded multisite trials in pediatric psychopharmacology
AU - Vitiello, Benedetto
N1 - Funding Information:
The Pediatric Bipolar Collaborative Mood Stabilizer Trial is a randomized clinical trial of the efficacy of lithium and valproate, used as monotherapy, for children and adolescents with manic bipolar disorder. This trial, which uses a double-blind design with a placebo control group, is funded by NIMH grants to the University of Cincinnati (R. Kowatch), Case Western Reserve University (R. Findling), and the University of Wisconsin at Milwaukee (R. Scheffer).
Funding Information:
The Studies to Advance Autism Research and Treatment Network was established in 2002–2003 under a cooperative agreement funded by NIMH, the National Institute of Child Health and Human Development, the National Institute of Neurological Disorders and Stroke, and the National Institute of Deafness and Communicative Disorders ( http://www.nimh.nih.gov/autismiacc/staart.cfm ). As part of this network, a multisite trial to test the efficacy of citalopram in autism was recently started ( http://www.clinicaltrials.gov/ct/show/NCT00086645?order=2 ).
PY - 2006/1
Y1 - 2006/1
N2 - In the last 10 years, the National Institute of Mental Health has funded a number of multisite clinical trials in pediatric psychopharmacology. Trials have been completed or are in progress in attention-deficit hyperactivity disorder, depression, autism, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and other anxiety disorders. Direct comparison between different treatment modalities, such as pharmacotherapy and psychotherapy, alone or in combination, has been the focus of a number of these studies, to inform clinicians and families of the relative therapeutic benefits of alternative interventions. This article presents a brief overview of these studies.
AB - In the last 10 years, the National Institute of Mental Health has funded a number of multisite clinical trials in pediatric psychopharmacology. Trials have been completed or are in progress in attention-deficit hyperactivity disorder, depression, autism, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and other anxiety disorders. Direct comparison between different treatment modalities, such as pharmacotherapy and psychotherapy, alone or in combination, has been the focus of a number of these studies, to inform clinicians and families of the relative therapeutic benefits of alternative interventions. This article presents a brief overview of these studies.
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U2 - 10.1016/j.chc.2005.08.010
DO - 10.1016/j.chc.2005.08.010
M3 - Review article
C2 - 16321723
AN - SCOPUS:28444466915
SN - 1056-4993
VL - 15
SP - 1
EP - 12
JO - Child and Adolescent Psychiatric Clinics of North America
JF - Child and Adolescent Psychiatric Clinics of North America
IS - 1
ER -