An improved cold stress test for aging mice

Mark Talan, Bernard T. Engel

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Tolerance to cold stress is a simple and reliable test which can be used longitudinally to study age-related differences or changes in thermoregulation of C57BL/6J mice. Neither prior food deprivation nor permanently inserted thermoprobes are necessary conditions for eliciting reliable age differences. However, restraint during the test is important and does elicit reliable age differences.

Original languageEnglish (US)
Pages (from-to)79-86
Number of pages8
JournalExperimental Gerontology
Issue number2
StatePublished - 1984

ASJC Scopus subject areas

  • Biochemistry
  • Aging
  • Molecular Biology
  • Genetics
  • Endocrinology
  • Cell Biology


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