TY - BOOK
T1 - An evidence framework for genetic testing
AU - Committee on the Evidence Base for Genetic Testing
AU - Board on the Health of Select Populations
AU - Board on Health Care Services
AU - Health and Medicine Division
AU - National Academies of Sciences, Engineering, and Medicine
AU - BERG, ALFRED O.
AU - BERG, JONATHAN S.
AU - BROWN, CHESTER W.
AU - BURKE, WYLIE
AU - CALONGE, BRUCE N.
AU - CHUNG, WENDY K.
AU - CLINE, THOMAS W.
AU - DAVID, SEAN P.
AU - GARBER, JUDY E.
AU - GREEN, ROBERT C.
AU - MARTINEZ-AGOSTO, JULIAN A.
AU - PIPER, MARGARET A.
AU - RISCH, NEIL J.
AU - SCHWARTZ, J. S.
AU - VALLE, DAVID
AU - VEENSTRA, DAVID L.
AU - WEXLER, NANCY S.
N1 - Publisher Copyright:
© 2017 by the National Academy of Sciences. All rights reserved.
PY - 2017/4/21
Y1 - 2017/4/21
N2 - Advances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence Framework for Genetic Testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care.
AB - Advances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence Framework for Genetic Testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care.
UR - http://www.scopus.com/inward/record.url?scp=85029822477&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85029822477&partnerID=8YFLogxK
U2 - 10.17226/24632
DO - 10.17226/24632
M3 - Book
AN - SCOPUS:85029822477
SN - 0309453291
SN - 9780309453295
BT - An evidence framework for genetic testing
PB - National Academies Press
ER -