An evaluation of tween 80 effects on the survival and DNA repair in Escherichia coli following UV or gamma irradiation

Ruey K. Chi; J. J. Scocca; P. C. Huang

doi:10.1016/0027-5107(78)90072-6

An evaluation of tween 80 effects on the survival and DNA repair in Escherichia coli following UV or gamma irradiation

Ruey K. Chi
, J. J. Scocca
, P. C. Huang

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The notion that Tween 80 may be a DNA-repair inhibitor was tested with Escherichia coli. The results indicate that cell growth, colony-forming ability, and the rate and extent of removal of thymine-containing dimers from DNA are unchanged in the presence of Tween 80. We conclude that this detergent does not increase or diminish the effect of UV or gamma irradiation to bacteria.

Original language	English (US)
Pages (from-to)	1-8
Number of pages	8
Journal	Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Volume	49
Issue number	1
DOIs	https://doi.org/10.1016/0027-5107(78)90072-6
State	Published - Jan 1978
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Genetics
Health, Toxicology and Mutagenesis

Access to Document

10.1016/0027-5107(78)90072-6

Cite this

@article{da25f74a9781420a99939899cae63915,

title = "An evaluation of tween 80 effects on the survival and DNA repair in Escherichia coli following UV or gamma irradiation",

abstract = "The notion that Tween 80 may be a DNA-repair inhibitor was tested with Escherichia coli. The results indicate that cell growth, colony-forming ability, and the rate and extent of removal of thymine-containing dimers from DNA are unchanged in the presence of Tween 80. We conclude that this detergent does not increase or diminish the effect of UV or gamma irradiation to bacteria.",

author = "Chi, \{Ruey K.\} and Scocca, \{J. J.\} and Huang, \{P. C.\}",

note = "Funding Information: * This study waS supported by NIH grants ES2P0100454 and 5T01ES00034-13. Portion of these results was presented before the American Society Biological Chemistry meetings at San Francisco 1976 (Fed. Proc., 35, 1490, Abstr. 672). ** to whom to address correspondence",

year = "1978",

month = jan,

doi = "10.1016/0027-5107(78)90072-6",

language = "English (US)",

volume = "49",

pages = "1--8",

journal = "Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis",

issn = "0027-5107",

publisher = "Elsevier BV",

number = "1",

}

TY - JOUR

T1 - An evaluation of tween 80 effects on the survival and DNA repair in Escherichia coli following UV or gamma irradiation

AU - Chi, Ruey K.

AU - Scocca, J. J.

AU - Huang, P. C.

N1 - Funding Information: * This study waS supported by NIH grants ES2P0100454 and 5T01ES00034-13. Portion of these results was presented before the American Society Biological Chemistry meetings at San Francisco 1976 (Fed. Proc., 35, 1490, Abstr. 672). ** to whom to address correspondence

PY - 1978/1

Y1 - 1978/1

N2 - The notion that Tween 80 may be a DNA-repair inhibitor was tested with Escherichia coli. The results indicate that cell growth, colony-forming ability, and the rate and extent of removal of thymine-containing dimers from DNA are unchanged in the presence of Tween 80. We conclude that this detergent does not increase or diminish the effect of UV or gamma irradiation to bacteria.

AB - The notion that Tween 80 may be a DNA-repair inhibitor was tested with Escherichia coli. The results indicate that cell growth, colony-forming ability, and the rate and extent of removal of thymine-containing dimers from DNA are unchanged in the presence of Tween 80. We conclude that this detergent does not increase or diminish the effect of UV or gamma irradiation to bacteria.

UR - https://www.scopus.com/pages/publications/0017927712

UR - https://www.scopus.com/pages/publications/0017927712#tab=citedBy

U2 - 10.1016/0027-5107(78)90072-6

DO - 10.1016/0027-5107(78)90072-6

M3 - Article

C2 - 340938

AN - SCOPUS:0017927712

SN - 0027-5107

VL - 49

SP - 1

EP - 8

JO - Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

JF - Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

IS - 1

ER -

An evaluation of tween 80 effects on the survival and DNA repair in Escherichia coli following UV or gamma irradiation

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this