An enzyme-linked immunosorbent assay (ELISA) was developed for the detection of thyroglobulin antibodies. The ELISA was compared with an indirect hemagglutination technique using thyroglobulin coupled to human group O erythrocytes with chromic chloride. The overall correlation between the two techniques was 0.82 (P < 0.001). ELISA proved to be suitable for large-scale screening, as all reagents are stable, with a long shelf life. However, because of its lower sensitivity, it will probably not as yet replace the chromic chloride IHA test.
|Number of pages
|Proceedings of the Society for Experimental Biology and Medicine
|Published - Mar 1980
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology