An Antimitotic and Antivascular Agent BPR0L075 Overcomes Multidrug Resistance and Induces Mitotic Catastrophe in Paclitaxel-Resistant Ovarian Cancer Cells

Medicine and Dentistry

• Ovarian Cancer 100%
• Cancer Cell 100%
• Paclitaxel 100%
• Multidrug Resistance 100%
• Vascular-Targeting Agent 100%
• Antimitotic Agent 100%
• Cell Death 33%
• Programmed Cell Death 16%
• Cytotoxicity 16%
• Poly ADP Ribose Polymerase 16%
• Survivin 16%
• Tubulin 16%
• Epileptic Absence 8%
• Effusion 8%
• Immunoblotting 8%
• IC50 8%
• Upregulation 8%
• Caspase 3 8%
• Microtubule 8%
• Cell Cycle 8%
• Antiproliferative Activity 8%
• Cell Cycle M Phase 8%
• Cyclin B1 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Paclitaxel 100%
• Multiple Drug Resistance 100%
• Ovary Cancer 100%
• Vascular Targeting Agent 100%
• Antimitotic Agent 100%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase 16%
• Tubulin 16%
• Survivin 16%
• Epileptic Absence 8%
• Western Blot 8%
• Effusion 8%
• Cytotoxicity 8%
• IC50 8%
• Caspase 3 8%
• Cyclin B1 8%

Keyphrases

• MPM-2 25%
• BubR1 25%
• Alternative Cell Death 12%
• P-class Groups 12%