Amygdala-frontal interactions and reward expectancy

Peter C. Holland, Michela Gallagher

Research output: Contribution to journalReview articlepeer-review

313 Scopus citations


Recent evidence indicates that networks including the amygdala and prefrontal cortex provide a key interface between affect and cognition. Converging evidence from rodents, humans, and non-human primates indicates that interconnections between the basolateral complex of the amygdala and the orbitofrontal cortex are crucial to the formation and use of expectancies of reinforcers in the guidance of goal-directed behavior.

Original languageEnglish (US)
Pages (from-to)148-155
Number of pages8
JournalCurrent Opinion in Neurobiology
Issue number2
StatePublished - Apr 2004


  • BLA
  • Basolateral amygdala
  • CS
  • Conditioned stimulus
  • Functional magnetic resonance imaging
  • OFC
  • Orbitofrontal cortex
  • fMRI

ASJC Scopus subject areas

  • General Neuroscience


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