Amniotic Fluid Embolism

Irene Stafford, Jeanne Sheffield

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations


Amniotic fluid embolism is a catastrophic syndrome occurring during labor and delivery or immediately postpartum. Although presenting symptoms may vary, common clinical features include shortness of breath, altered mental status followed by sudden cardiovascular collapse, disseminated intravascular coagulation, and maternal death. It was first recognized as a syndrome in 1941, when two investigators described fetal mucin and squamous cells during postmortem examination of the pulmonary vasculature in women who had unexplained obstetric deaths. Since then, many studies, case reports, and series have been published in an attempt to elucidate the etiology, risk factors, and pathogenesis of this mysterious obstetric complication.

Original languageEnglish (US)
Pages (from-to)545-553
Number of pages9
JournalObstetrics and Gynecology Clinics of North America
Issue number3
StatePublished - Sep 1 2007
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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