Alzheimer disease and the prion disorders amyloid β-protein and prion protein amyloidoses

Donald L. Price; David R. Borchelt; Sangram S. Sisodia

doi:10.1073/pnas.90.14.6381

Alzheimer disease and the prion disorders amyloid β-protein and prion protein amyloidoses

Donald L. Price, David R. Borchelt, Sangram S. Sisodia

School of Medicine

Research output: Contribution to journal › Review article › peer-review

56 Scopus citations

Abstract

Alzheimer disease and the prion disorders/spongiform encephalopathies share many common features. These chronic, progressive, sometimes familial diseases of the central nervous system are characterized by the presence of different types of amyloid deposits in the brain. This review provides a perspective on these two types of neurodegenerative disorders.

Original language	English (US)
Pages (from-to)	6381-6384
Number of pages	4
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	90
Issue number	14
DOIs	https://doi.org/10.1073/pnas.90.14.6381
State	Published - Jul 15 1993

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title = "Alzheimer disease and the prion disorders amyloid β-protein and prion protein amyloidoses",

abstract = "Alzheimer disease and the prion disorders/spongiform encephalopathies share many common features. These chronic, progressive, sometimes familial diseases of the central nervous system are characterized by the presence of different types of amyloid deposits in the brain. This review provides a perspective on these two types of neurodegenerative disorders.",

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Alzheimer disease and the prion disorders amyloid β-protein and prion protein amyloidoses

Abstract

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