Abstract
In 1954, University Federation for Animal Welfare (UFAW) engaged two scientists, William Russell and Rex Burch, to write a book on humane experimental technique. The book, “The Principles of Humane Experimental Technique,” published in 19591 demonstrated with great clarity the impact of humanity on scientific experiments and comprehensively described why humane techniques are important, not only ethically, but also scientifically. They introduced essential methodology to achieve humane experimental technique. This methodology encompassed the concepts of refinement, reduction, and replacement - the Three Rs as applied to experimental protocols (see also Chapter 18).
| Original language | English (US) |
|---|---|
| Title of host publication | Handbook of Laboratory Animal Science, Second Edition |
| Subtitle of host publication | Essential Principles and Practices |
| Publisher | CRC Press |
| Pages | 539-545 |
| Number of pages | 7 |
| Volume | 1 |
| ISBN (Electronic) | 9781420040913 |
| ISBN (Print) | 0849310865, 9780849310867 |
| State | Published - Jan 1 2002 |
ASJC Scopus subject areas
- General Medicine
- General Veterinary
- Pharmacology, Toxicology and Pharmaceutics(all)