Alterations in consummatory behavior of mice produced by dietary exposure to inorganic lead

John H. Morrison; David S. Olton; Alan M. Goldberg; Ellen K. Silbergeld

doi:10.1002/dev.420080503

Alterations in consummatory behavior of mice produced by dietary exposure to inorganic lead

John H. Morrison, David S. Olton, Alan M. Goldberg, Ellen K. Silbergeld

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Mice suckled by mothers given tap water and by mothers given a 5 mg/ml lead acetate solution during lactation were given a choice between tap water and a lead acetate solution after lactation. All offspring demonstrated an immediate aversion to the lead acetate solution. The offspring from the mothers receiving lead acetate during lactation demonstrated a greater aversion to the lead acetate solution than did the offspring from mothers receiving tap water. In addition, the lead acetate offspring drank more total fluid (tap water plus lead acetate solution) after weaning than the control offspring. The results indicate both learned and unlearned changes in motivation for fluid following ingestion of lead via the mother's milk in infancy.

Original language	English (US)
Pages (from-to)	389-396
Number of pages	8
Journal	Developmental Psychobiology
Volume	8
Issue number	5
DOIs	https://doi.org/10.1002/dev.420080503
State	Published - Sep 1975

ASJC Scopus subject areas

Developmental and Educational Psychology
Developmental Neuroscience
Developmental Biology
Behavioral Neuroscience

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title = "Alterations in consummatory behavior of mice produced by dietary exposure to inorganic lead",

abstract = "Mice suckled by mothers given tap water and by mothers given a 5 mg/ml lead acetate solution during lactation were given a choice between tap water and a lead acetate solution after lactation. All offspring demonstrated an immediate aversion to the lead acetate solution. The offspring from the mothers receiving lead acetate during lactation demonstrated a greater aversion to the lead acetate solution than did the offspring from mothers receiving tap water. In addition, the lead acetate offspring drank more total fluid (tap water plus lead acetate solution) after weaning than the control offspring. The results indicate both learned and unlearned changes in motivation for fluid following ingestion of lead via the mother's milk in infancy.",

author = "Morrison, {John H.} and Olton, {David S.} and Goldberg, {Alan M.} and Silbergeld, {Ellen K.}",

year = "1975",

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AU - Olton, David S.

AU - Goldberg, Alan M.

AU - Silbergeld, Ellen K.

PY - 1975/9

Y1 - 1975/9

N2 - Mice suckled by mothers given tap water and by mothers given a 5 mg/ml lead acetate solution during lactation were given a choice between tap water and a lead acetate solution after lactation. All offspring demonstrated an immediate aversion to the lead acetate solution. The offspring from the mothers receiving lead acetate during lactation demonstrated a greater aversion to the lead acetate solution than did the offspring from mothers receiving tap water. In addition, the lead acetate offspring drank more total fluid (tap water plus lead acetate solution) after weaning than the control offspring. The results indicate both learned and unlearned changes in motivation for fluid following ingestion of lead via the mother's milk in infancy.

AB - Mice suckled by mothers given tap water and by mothers given a 5 mg/ml lead acetate solution during lactation were given a choice between tap water and a lead acetate solution after lactation. All offspring demonstrated an immediate aversion to the lead acetate solution. The offspring from the mothers receiving lead acetate during lactation demonstrated a greater aversion to the lead acetate solution than did the offspring from mothers receiving tap water. In addition, the lead acetate offspring drank more total fluid (tap water plus lead acetate solution) after weaning than the control offspring. The results indicate both learned and unlearned changes in motivation for fluid following ingestion of lead via the mother's milk in infancy.

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Alterations in consummatory behavior of mice produced by dietary exposure to inorganic lead

Abstract

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