Abstract
In recent years, more 3D protein structures have become available, which has made the analysis of large molecular structuresmuch easier.There is a strong demand for geometric models for the study of protein-related interactions. Alpha shape and Delaunay triangulation are powerful tools to represent protein structures and have advantages in characterizing the surface curvature and atom contacts. This review presents state-of-the-art applications of alpha shape and Delaunay triangulation in the studies on protein-DNA, protein-protein, protein-ligand interactions and protein structure analysis.
| Original language | English (US) |
|---|---|
| Article number | bbs077 |
| Pages (from-to) | 54-64 |
| Number of pages | 11 |
| Journal | Briefings in bioinformatics |
| Volume | 15 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2014 |
| Externally published | Yes |
Keywords
- Alpha shape
- Delaunay triangulation
- Protein structure analysis
- Protein-DNA interactions
- Protein-ligand interactions
- Protein-protein interactions
ASJC Scopus subject areas
- Information Systems
- Molecular Biology