Aging of protein molecules: lens crystallins as a model system

J. Samuel Zigler, John Goosey

Research output: Contribution to journalReview articlepeer-review

47 Scopus citations


As a result of the unique development and protein metabolism of the vertebrate lens this organ probably contains the body's longest-lived proteins. The major structural proteins of the lens, the crystallins, offer unusual advantages for studying a wide variety of age-related structural modifications to proteins.

Original languageEnglish (US)
Pages (from-to)133-136
Number of pages4
JournalTrends in biochemical sciences
Issue numberC
StatePublished - 1981

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology


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