Aging as a glitch in the matrix

Seung Mo Jin; Jennifer H. Elisseeff

doi:10.1038/s43587-025-01009-7

Aging as a glitch in the matrix

Seung Mo Jin
, Jennifer H. Elisseeff

Whiting School of Engineering

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Yi and colleagues demonstrate that age-induced degradation of extracellular matrix generates elastin-derived fragments that activate the innate and adaptive immune system, which evokes systemic inflammaging.

Original language	English (US)
Pages (from-to)	2365-2366
Number of pages	2
Journal	Nature Aging
Volume	5
Issue number	12
DOIs	https://doi.org/10.1038/s43587-025-01009-7
State	Published - Dec 2025

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Aging
Geriatrics and Gerontology

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Aging as a glitch in the matrix

Abstract

ASJC Scopus subject areas

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