TY - JOUR
T1 - Aging and Alzheimer Disease in People with Mental Retardation
AU - Zigman, Warren B.
AU - Schupf, Nicole
AU - Zigman, April
AU - Silverman, Wayne
N1 - Funding Information:
HD24170, PO1 HD22634, and ROI AGO9439 from the National Institutes of Health, and Grant IIRG-90-067 from the Alzheimer’s Association. The insightful comments by Dr. Wisniewski and Dr. Arthur Dalton are gratefully acknowledged.
Funding Information:
Our activities described herein are part of a large Institute-wide program studying aging processes in people with mental retardation and developmental disabilities. under the overall direction of Henry M. Wisniewski, M.D., Ph.D. This program is supported by funds provided by New York State through its Ofice of Mental Retardation and Developmental Disabilities, as well as by Grants R29
PY - 1993/1/1
Y1 - 1993/1/1
N2 - This chapter describes Alzheimer disease, clinically and pathologically. It illustrates the relationship between Down syndrome and Alzheimer disease and integrates this relationship with an overall plan of research and service for elderly people with mental retardation. There is a need for training and treatment of the staff to recognize the early signs and symptoms of new secondary disabilities related to the aging process. Treatable conditions, such as depression, thyroid dysfunction, or systemic infections can produce symptoms resembling Alzheimer dementia. Therefore, if behavioral deterioration is because of one of these conditions, proper treatment can be initiated, and the condition ameliorated or reversed. There is a pressing need to develop day and residential programs that can provide appropriate care for dementing clients, who cannot be maintained in their current programs or family circumstances.
AB - This chapter describes Alzheimer disease, clinically and pathologically. It illustrates the relationship between Down syndrome and Alzheimer disease and integrates this relationship with an overall plan of research and service for elderly people with mental retardation. There is a need for training and treatment of the staff to recognize the early signs and symptoms of new secondary disabilities related to the aging process. Treatable conditions, such as depression, thyroid dysfunction, or systemic infections can produce symptoms resembling Alzheimer dementia. Therefore, if behavioral deterioration is because of one of these conditions, proper treatment can be initiated, and the condition ameliorated or reversed. There is a pressing need to develop day and residential programs that can provide appropriate care for dementing clients, who cannot be maintained in their current programs or family circumstances.
UR - http://www.scopus.com/inward/record.url?scp=0002999538&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0002999538&partnerID=8YFLogxK
U2 - 10.1016/S0074-7750(08)60188-3
DO - 10.1016/S0074-7750(08)60188-3
M3 - Article
AN - SCOPUS:0002999538
SN - 0074-7750
VL - 19
SP - 41
EP - 70
JO - International Review of Research in Mental Retardation
JF - International Review of Research in Mental Retardation
IS - C
ER -