Age-specific incidence rates for cytogenetically-defined subtypes of acute myeloid leukaemia

A. V. Moorman; E. Roman; R. A. Cartwright; G. J. Morgan

doi:10.1038/sj.bjc.6600195

Age-specific incidence rates for cytogenetically-defined subtypes of acute myeloid leukaemia

A. V. Moorman, E. Roman, R. A. Cartwright, G. J. Morgan

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

It is generally considered that most cancers arise following the accumulation of several genetic events and that as a consequence its incidence increases with age. We report a cytogenetic subgroup of acute myeloid leukaemia whose incidence is independent of age. This observation indicates that acute myeloid leukaemia can develop via multiple pathways, and underlines the importance of cytogenetics in understanding this disease.

Original language	English (US)
Pages (from-to)	1061-1063
Number of pages	3
Journal	British journal of cancer
Volume	86
Issue number	7
DOIs	https://doi.org/10.1038/sj.bjc.6600195
State	Published - 2002
Externally published	Yes

Keywords

Acute myeloid leukaemia
Aetiology
Age
Chromosomal abnormalities
Cytogenetics
Incidence rate

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1038/sj.bjc.6600195

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title = "Age-specific incidence rates for cytogenetically-defined subtypes of acute myeloid leukaemia",

abstract = "It is generally considered that most cancers arise following the accumulation of several genetic events and that as a consequence its incidence increases with age. We report a cytogenetic subgroup of acute myeloid leukaemia whose incidence is independent of age. This observation indicates that acute myeloid leukaemia can develop via multiple pathways, and underlines the importance of cytogenetics in understanding this disease.",

keywords = "Acute myeloid leukaemia, Aetiology, Age, Chromosomal abnormalities, Cytogenetics, Incidence rate",

author = "Moorman, {A. V.} and E. Roman and Cartwright, {R. A.} and Morgan, {G. J.}",

note = "Funding Information: This work was supported by a research grant from the Leukaemia Research Fund. We thank the following for providing cytogenetic data: South West Regional Cytogenetics Centre, Bristol (Mrs C Kitchen); Cytogenetics Department, St James University Hospital, Leeds (Mrs H Dickinson); Oncology Cytogenetics Service, Christie Hospital, Manchester (Mr N Telford); Northern Genetics Service,",

year = "2002",

doi = "10.1038/sj.bjc.6600195",

language = "English (US)",

volume = "86",

pages = "1061--1063",

journal = "British journal of cancer",

issn = "0007-0920",

publisher = "Nature Publishing Group",

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TY - JOUR

T1 - Age-specific incidence rates for cytogenetically-defined subtypes of acute myeloid leukaemia

AU - Moorman, A. V.

AU - Roman, E.

AU - Cartwright, R. A.

AU - Morgan, G. J.

N1 - Funding Information: This work was supported by a research grant from the Leukaemia Research Fund. We thank the following for providing cytogenetic data: South West Regional Cytogenetics Centre, Bristol (Mrs C Kitchen); Cytogenetics Department, St James University Hospital, Leeds (Mrs H Dickinson); Oncology Cytogenetics Service, Christie Hospital, Manchester (Mr N Telford); Northern Genetics Service,

PY - 2002

Y1 - 2002

N2 - It is generally considered that most cancers arise following the accumulation of several genetic events and that as a consequence its incidence increases with age. We report a cytogenetic subgroup of acute myeloid leukaemia whose incidence is independent of age. This observation indicates that acute myeloid leukaemia can develop via multiple pathways, and underlines the importance of cytogenetics in understanding this disease.

AB - It is generally considered that most cancers arise following the accumulation of several genetic events and that as a consequence its incidence increases with age. We report a cytogenetic subgroup of acute myeloid leukaemia whose incidence is independent of age. This observation indicates that acute myeloid leukaemia can develop via multiple pathways, and underlines the importance of cytogenetics in understanding this disease.

KW - Acute myeloid leukaemia

KW - Aetiology

KW - Age

KW - Chromosomal abnormalities

KW - Cytogenetics

KW - Incidence rate

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SP - 1061

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JO - British journal of cancer

JF - British journal of cancer

IS - 7

ER -

Age-specific incidence rates for cytogenetically-defined subtypes of acute myeloid leukaemia

Abstract

Keywords

ASJC Scopus subject areas

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