Age-related decline in cold tolerance can be retarded by brain stimulation

M. I. Talan, B. T. Engel, J. R. Whitaker

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


The sharp decline in capacity of old C57BL/6J male mice to maintain body temperature during 3-hr cold exposure can be delayed and even partly restored after 15, 30-min, daily sessions of hypothalamic self-stimulation. In control experiments it was demonstrated that electrical stimulation of "rewarding" areas of hypothalamus itself is sufficient for improvement of the age-related deterioration of thermoregulatory ability.

Original languageEnglish (US)
Pages (from-to)969-973
Number of pages5
JournalPhysiology and Behavior
Issue number6
StatePublished - Dec 1984


  • "Rewarding"areas of hypothalamus
  • Age
  • Cold exposure
  • Intracranial self-stimulation
  • Mice
  • Thermoregulation

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience


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