Aerosol Immunization of Humans with Inactivated Parainfluenza Type 2 Vaccine

F. M. Wigley, M. H. Fruchtman, R. H. Waldman

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


The antibody response was compared in 40 volunteers who were immunized with parainfluenza Type 2 vaccine, either subcutaneously or by aerosol, and in 16 controls. The neutralizing-antibody response in respiratory secretions was of greater magnitude in the aerosol group than in the other groups. In both the aerosol and the subcutaneous groups there was a significant rise in serum antibody. The respiratory-secretion antibody was found in the IgA class.

Original languageEnglish (US)
Pages (from-to)1250-1253
Number of pages4
JournalNew England Journal of Medicine
Issue number23
StatePublished - Dec 3 1970
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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