Adverse reactions to pneumococcal polysaccharide vaccine in children

Neal A. Halsey, John S. Spika, Gary M. L Um, Gerald S. S Chiffman, Brian A. Lauer

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Polyvalent pneumococcal vaccine (Pneumovax, Merck, Sharpe & Dome) has been shown to be safe and effective in clinical trials of normal adults.1-6 Side effects are infrequent and reactions, when they occur, are generally mild. During a vaccine study of children with nephrotic syndrome we observed an unexpectedly high frequency of vaccine reactions which correlated with antibody response. One child with a severe reaction is reported in detail.

Original languageEnglish (US)
Pages (from-to)34-36
Number of pages3
JournalPediatric Infectious Disease
Issue number1
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)


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