TY - JOUR
T1 - Adverse effects of rifampin
AU - Grosset, Jacques
AU - Leventis, Stephanie
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1983/7
Y1 - 1983/7
N2 - Rifampin has proved to be a valuable antibiotic with relatively few major adverse effects. Its toxicity is predominantly hepatic and immunoallergic in character. While hepatic toxicity is dose related and has been observed mainly in patients with underlying liver disease, the immunoallergic effects are usually associated with intermittent or prolonged therapy. These immunoallergic effects may be minor (a cutaneous, gastrointestinal, or influenzalike syndrome) or major (hemolytic anemia, shock, or acute renal failure).
AB - Rifampin has proved to be a valuable antibiotic with relatively few major adverse effects. Its toxicity is predominantly hepatic and immunoallergic in character. While hepatic toxicity is dose related and has been observed mainly in patients with underlying liver disease, the immunoallergic effects are usually associated with intermittent or prolonged therapy. These immunoallergic effects may be minor (a cutaneous, gastrointestinal, or influenzalike syndrome) or major (hemolytic anemia, shock, or acute renal failure).
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U2 - 10.1093/clinids/5.Supplement_3.S440
DO - 10.1093/clinids/5.Supplement_3.S440
M3 - Article
C2 - 6356277
AN - SCOPUS:84857002710
SN - 0162-0886
VL - 5
SP - S440-S446
JO - Reviews of infectious diseases
JF - Reviews of infectious diseases
ER -