Adverse effects of rifampin

Jacques Grosset, Stephanie Leventis

Research output: Contribution to journalArticlepeer-review

138 Scopus citations


Rifampin has proved to be a valuable antibiotic with relatively few major adverse effects. Its toxicity is predominantly hepatic and immunoallergic in character. While hepatic toxicity is dose related and has been observed mainly in patients with underlying liver disease, the immunoallergic effects are usually associated with intermittent or prolonged therapy. These immunoallergic effects may be minor (a cutaneous, gastrointestinal, or influenzalike syndrome) or major (hemolytic anemia, shock, or acute renal failure).

Original languageEnglish (US)
Pages (from-to)S440-S446
JournalReviews of infectious diseases
StatePublished - Jul 1983
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)


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