Advances in vaccine technology

Julie Ahn; Simon R Best; David E Tunkel

doi:10.1007/978-3-319-63823-2_4

Advances in vaccine technology

Julie Ahn, Simon R Best, David E Tunkel

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Human papillomaviruses (HPVs) are the causative agent for recurrent respiratory papillomatosis, cancer of the cervix, and squamous cell carcinoma of the head and neck. Vaccines are available to prevent infection with several of the HPV types that are responsible for causing these serious diseases. This chapter discusses the development, successes, and limitations of these prophylactic L1-based vaccines. Potential for L2-based vaccines to provide broad coverage to prevent infection with many HPV types is also discussed. Finally, research into treatment of established HPV infection and resultant disease using therapeutic vaccines is outlined.

Original language	English (US)
Title of host publication	Recurrent Respiratory Papillomatosis
Publisher	Springer International Publishing
Pages	45-58
Number of pages	14
ISBN (Electronic)	9783319638232
ISBN (Print)	9783319638225
DOIs	https://doi.org/10.1007/978-3-319-63823-2_4
State	Published - Jan 1 2017

Keywords

Cervarix
Gardasil
Human papillomavirus
Recurrent respiratory papillomatosis
Vaccine

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-3-319-63823-2_4

Cite this

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abstract = "Human papillomaviruses (HPVs) are the causative agent for recurrent respiratory papillomatosis, cancer of the cervix, and squamous cell carcinoma of the head and neck. Vaccines are available to prevent infection with several of the HPV types that are responsible for causing these serious diseases. This chapter discusses the development, successes, and limitations of these prophylactic L1-based vaccines. Potential for L2-based vaccines to provide broad coverage to prevent infection with many HPV types is also discussed. Finally, research into treatment of established HPV infection and resultant disease using therapeutic vaccines is outlined.",

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AU - Best, Simon R

AU - Tunkel, David E

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AB - Human papillomaviruses (HPVs) are the causative agent for recurrent respiratory papillomatosis, cancer of the cervix, and squamous cell carcinoma of the head and neck. Vaccines are available to prevent infection with several of the HPV types that are responsible for causing these serious diseases. This chapter discusses the development, successes, and limitations of these prophylactic L1-based vaccines. Potential for L2-based vaccines to provide broad coverage to prevent infection with many HPV types is also discussed. Finally, research into treatment of established HPV infection and resultant disease using therapeutic vaccines is outlined.

KW - Cervarix

KW - Gardasil

KW - Human papillomavirus

KW - Recurrent respiratory papillomatosis

KW - Vaccine

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BT - Recurrent Respiratory Papillomatosis

PB - Springer International Publishing

ER -

Advances in vaccine technology

Abstract

Keywords

ASJC Scopus subject areas

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