TY - JOUR
T1 - Advances in understanding the development of the nervous system
AU - Singer, H. S.
AU - Chiu, A. Y.
AU - Meiri, F. K.
AU - Morell, P.
AU - Nelson, P. G.
AU - Tennekoon, G.
PY - 1994
Y1 - 1994
N2 - Over the past several years remarkable progress has been made towards unraveling the complex mechanisms that regulate neuronal development. Because the end results of abnormalities in brain development are often developmental disabilities, it is timely to review several recent advances in the field of neurobiology. This review, with contributions from several co-authors, provides a synopsis of breakthroughs from the fields of embryology, cell biology, and molecular genetics that hold promise for exciting clinical application. This article is arranged to reflect the stages of normal development. Understanding the mechanisms underlying neuronal induction, regional specification, neuronal specification, migration, axonal growth, neurotrophic factors, and myelination should clarify the pathophysiology of numerous neurological disorders, and provide new insights into their treatment.
AB - Over the past several years remarkable progress has been made towards unraveling the complex mechanisms that regulate neuronal development. Because the end results of abnormalities in brain development are often developmental disabilities, it is timely to review several recent advances in the field of neurobiology. This review, with contributions from several co-authors, provides a synopsis of breakthroughs from the fields of embryology, cell biology, and molecular genetics that hold promise for exciting clinical application. This article is arranged to reflect the stages of normal development. Understanding the mechanisms underlying neuronal induction, regional specification, neuronal specification, migration, axonal growth, neurotrophic factors, and myelination should clarify the pathophysiology of numerous neurological disorders, and provide new insights into their treatment.
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U2 - 10.1097/00019052-199404000-00012
DO - 10.1097/00019052-199404000-00012
M3 - Editorial
C2 - 8019661
AN - SCOPUS:0028281887
SN - 1350-7540
VL - 7
SP - 153
EP - 159
JO - Current opinion in neurology
JF - Current opinion in neurology
IS - 2
ER -