Adult Limb Deformity Reconstruction in Osteogenesis Imperfecta

Stephen Jacobsen, Paul D. Sponseller

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Patients with osteogenesis imperfecta (OI) may continue to suffer from the sequelae of the disease, such as limb deformities, chronic non-unions, pain and functional impairment, throughout adulthood. In these adult patients, surgical limb reconstruction can be used to address the sequelae of OI and prevent further damage. During limb reconstruction, surgical techniques including multiple osteotomies stabilized by strut allografts, implants and other graft material can be applied safely and effectively, with a relatively low rate of adverse outcomes. Patients undergoing limb reconstruction procedures report an increase in functional capacity and a decrease in discomfort. Complications include migration of implants and non-union of osteotomies, which can usually be addressed successfully through a revision procedure.

Original languageEnglish (US)
Title of host publicationOsteogenesis Imperfecta
Subtitle of host publicationA Translational Approach to Brittle Bone Disease
PublisherElsevier Inc.
Number of pages7
ISBN (Print)9780123971654
StatePublished - Sep 2013


  • Adults
  • Allografts
  • Limb reconstruction
  • Osteogenesis imperfecta
  • Osteotomies

ASJC Scopus subject areas

  • General Dentistry
  • General Medicine


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