Adjuvant endocrine therapy

Karen Smith; Vered Stearns

doi:10.1016/B978-0-323-35955-9.00054-4

Adjuvant endocrine therapy

Karen Smith, Vered Stearns

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Endocrine therapy is a key component of the adjuvant treatment of early-stage breast cancer. In this chapter, we review the current approach to adjuvant endocrine therapy for early-stage invasive breast cancer and ductal carcinoma in situ. We also review key trials leading to the development of current treatments and review toxicities and unanswered questions. Emphasis is placed on differences in the approaches to adjuvant endocrine therapy in pre- and postmenopausal women.

Original language	English (US)
Title of host publication	The Breast
Subtitle of host publication	Comprehensive Management of Benign and Malignant Diseases
Publisher	Elsevier Inc.
Pages	736-751.e4
ISBN (Print)	9780323359559
DOIs	https://doi.org/10.1016/B978-0-323-35955-9.00054-4
State	Published - 2018

Keywords

Adjuvant endocrine therapy
Aromatase inhibitor
Breast cancer
Ovarian suppression
Tamoxifen

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1016/B978-0-323-35955-9.00054-4

Cite this

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abstract = "Endocrine therapy is a key component of the adjuvant treatment of early-stage breast cancer. In this chapter, we review the current approach to adjuvant endocrine therapy for early-stage invasive breast cancer and ductal carcinoma in situ. We also review key trials leading to the development of current treatments and review toxicities and unanswered questions. Emphasis is placed on differences in the approaches to adjuvant endocrine therapy in pre- and postmenopausal women.",

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AB - Endocrine therapy is a key component of the adjuvant treatment of early-stage breast cancer. In this chapter, we review the current approach to adjuvant endocrine therapy for early-stage invasive breast cancer and ductal carcinoma in situ. We also review key trials leading to the development of current treatments and review toxicities and unanswered questions. Emphasis is placed on differences in the approaches to adjuvant endocrine therapy in pre- and postmenopausal women.

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KW - Ovarian suppression

KW - Tamoxifen

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ER -

Adjuvant endocrine therapy

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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