Adherence to the Healthy Eating Index and Alternative Healthy Eating Index dietary patterns and mortality from all causes, cardiovascular disease and cancer: a meta-analysis of observational studies

S. Onvani, F. Haghighatdoost, P. J. Surkan, B. Larijani, L. Azadbakht

Research output: Contribution to journalArticlepeer-review

85 Scopus citations

Abstract

Background: This meta-analysis investigated the association of diet quality indices, as assessed by HEI and AHEI, and the risk of all-cause, cardiovascular and cancer mortality. Methods: We used PubMed, ISI Web of Science and Google Scholar to search for eligible articles published before July 2015. A total of 12 cohort studies (38 reports) and one cross-sectional study (three reports) met the inclusion criteria and were included in our meta-analysis. Results: The highest level of adherence to the Healthy Eating Index (HEI) and Alternative Healthy Eating Index (AHEI) was significantly associated with a reduced risk of all-cause mortality [relative risk (RR) = 0.77, 95% confidence intterval (CI) = 0.76–0.78], cardiovascular mortality (RR = 0.77, 95% CI = 0.74–0.80) and cancer mortality (RR = 0.83, 95% CI = 0.81–0.86). Egger regression tests provided no evidence of publication bias. Conclusions: The present study indicates that high adherence to HEI and AHEI dietary patterns, indicating high diet quality, are associated with reduced risk of all-cause mortality (as well as cardiovascular mortality and cancer mortality).

Original languageEnglish (US)
Pages (from-to)216-226
Number of pages11
JournalJournal of Human Nutrition and Dietetics
Volume30
Issue number2
DOIs
StatePublished - Apr 1 2017

Keywords

  • Alternative Healthy Eating Index
  • Healthy Eating Index
  • cancer
  • cardiovascular
  • mortality

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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