TY - JOUR
T1 - Addressing the post-acute sequelae of SARS-CoV-2 infection
T2 - a multidisciplinary model of care
AU - Parker, Ann M.
AU - Brigham, Emily
AU - Connolly, Bronwen
AU - McPeake, Joanne
AU - Agranovich, Anna V.
AU - Kenes, Michael T.
AU - Casey, Kelly
AU - Reynolds, Cynthia
AU - Schmidt, Konrad F.R.
AU - Kim, Soo Yeon
AU - Kaplin, Adam
AU - Sevin, Carla M.
AU - Brodsky, Martin B.
AU - Turnbull, Alison E.
N1 - Publisher Copyright:
© 2021 Elsevier Ltd
PY - 2021/11
Y1 - 2021/11
N2 - As of July 31, 2021, SARS-CoV-2 had infected almost 200 million people worldwide. The growing burden of survivorship is substantial in terms of the complexity of long-term health effects and the number of people affected. Persistent symptoms have been reported in patients with both mild and severe acute COVID-19, including those admitted to the intensive care unit (ICU). Early reports on the post-acute sequelae of SARS-CoV-2 infection (PASC) indicate that fatigue, dyspnoea, cough, headache, loss of taste or smell, and cognitive or mental health impairments are among the most common symptoms. These complex, multifactorial impairments across the domains of physical, cognitive, and mental health require a coordinated, multidisciplinary approach to management. Decades of research on the multifaceted needs of and models of care for patients with post-intensive care syndrome provide a framework for the development of PASC clinics to address the immediate needs of both hospitalised and non-hospitalised survivors of COVID-19. Such clinics could also provide a platform for rigorous research into the natural history of PASC and the potential benefits of therapeutic interventions.
AB - As of July 31, 2021, SARS-CoV-2 had infected almost 200 million people worldwide. The growing burden of survivorship is substantial in terms of the complexity of long-term health effects and the number of people affected. Persistent symptoms have been reported in patients with both mild and severe acute COVID-19, including those admitted to the intensive care unit (ICU). Early reports on the post-acute sequelae of SARS-CoV-2 infection (PASC) indicate that fatigue, dyspnoea, cough, headache, loss of taste or smell, and cognitive or mental health impairments are among the most common symptoms. These complex, multifactorial impairments across the domains of physical, cognitive, and mental health require a coordinated, multidisciplinary approach to management. Decades of research on the multifaceted needs of and models of care for patients with post-intensive care syndrome provide a framework for the development of PASC clinics to address the immediate needs of both hospitalised and non-hospitalised survivors of COVID-19. Such clinics could also provide a platform for rigorous research into the natural history of PASC and the potential benefits of therapeutic interventions.
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U2 - 10.1016/S2213-2600(21)00385-4
DO - 10.1016/S2213-2600(21)00385-4
M3 - Review article
C2 - 34678213
AN - SCOPUS:85118493645
SN - 2213-2600
VL - 9
SP - 1328
EP - 1341
JO - The Lancet Respiratory Medicine
JF - The Lancet Respiratory Medicine
IS - 11
ER -