Adaptation of physical stress in bone cortical defect healing

Edmund Y.S. Chao, John J. Elias, Nozomu Inoue

Research output: Chapter in Book/Report/Conference proceedingConference contribution


A canine tibia defect model was developed to investigate the mechanical-biological interaction during defect healing. The resultant model provides a quick healing period, large strain gradients, a plane symmetric strain distribution, and the ability to serve as a test-bed to investigate the efficacy of other factors. This article describes the model and proceeds to investigate the hypothesis that bone defect repair is influenced by the stress/strain distribution within the intact cortical bone surrounding the defect.

Original languageEnglish (US)
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Number of pages2
ISBN (Print)0791816117
StatePublished - Dec 1 1999
Event1999 Bioengineering Conference - Big Sky, MT, USA
Duration: Jun 16 1999Jun 20 1999


Other1999 Bioengineering Conference
CityBig Sky, MT, USA

ASJC Scopus subject areas

  • Engineering(all)


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