Acute transient cortical blindness due to seizure following cerebral angiography

C. Benjamin Newman, Courtney Schusse, Yin C. Hu, Cameron G. McDougall, Felipe C. Albuquerque

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Objective Transient cortical blindness (TCB) is reported as a rare complication of coronary and cerebral angiography. Angiography of the vertebral arteries carries the highest incidence of causing TCB. The etiology of this phenomenon is unknown. Clinical presentation A 42-year-old woman underwent treatment for an enlarging pseudoaneurysm of her vertebral artery. The patient had a brief complex seizure during angiography. Following the procedure, she experienced TCB. During this time, an electroencephalogram (EEG) showed seizure activity. This case represents the first recorded instance of abnormal EEG during angiography-associated TCB. Intervention The patient was immediately given intravenous lorazepam and phenytoin sodium. Her EEG returned to normal in the ensuing hours and subsequently her vision returned to normal. Conclusion We present the first reported case of abnormal EEG activity during angiography-associated TCB. We hypothesize that seizure activity is a possible underlying cause of angiography-induced TCB.

Original languageEnglish (US)
Pages (from-to)83-86
Number of pages4
JournalWorld neurosurgery
Issue number1
StatePublished - Jan 2011
Externally publishedYes


  • Cerebral angiography
  • Seizure
  • Transient cortical blindness

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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