TY - JOUR
T1 - Acute myeloid leukemia
T2 - Clinical Practice Guidelines in Oncology
AU - O'Donnell, Margaret R.
AU - Appelbaum, Frederick R.
AU - Baer, Maria R.
AU - Byrd, John C.
AU - Coutre, Steven E.
AU - Damon, Lloyd E.
AU - Erba, Harry P.
AU - Estey, Eli
AU - Foran, James
AU - Lancet, Jeffrey
AU - Maness, Lori J.
AU - Maslak, Peter G.
AU - Millenson, Michael
AU - Moore, Joseph O.
AU - Przepiorka, Donna
AU - Shami, Paul
AU - Smith, B. Douglas
AU - Stone, Richard M.
AU - Tallman, Martin S.
PY - 2006/1
Y1 - 2006/1
N2 - Approximately 11,960 people will be diagnosed with acute myeloid leukemia (AML) in 2005, and 9,000 patients will die of the disease. As the population ages, the incidence of AML, along with myelodysplasia, appears to be rising. Equally disturbing is the increasing incidence of treatment-related myelodysplasia and leukemia in survivors of tumors of childhood and young adulthood such as Hodgkin's disease, sarcomas, breast and testicular cancers, and lymphomas. Recent large clinical trials have highlighted the need for new, innovative strategies because outcomes for AML patients, particularly older patients, have not substantially changed in the past 3 decades.
AB - Approximately 11,960 people will be diagnosed with acute myeloid leukemia (AML) in 2005, and 9,000 patients will die of the disease. As the population ages, the incidence of AML, along with myelodysplasia, appears to be rising. Equally disturbing is the increasing incidence of treatment-related myelodysplasia and leukemia in survivors of tumors of childhood and young adulthood such as Hodgkin's disease, sarcomas, breast and testicular cancers, and lymphomas. Recent large clinical trials have highlighted the need for new, innovative strategies because outcomes for AML patients, particularly older patients, have not substantially changed in the past 3 decades.
KW - Acute myeloid leukemia
KW - Chemotherapeutic agents
KW - Cytogenetics
KW - Leukemia treatment
KW - NCCN Clinical Practice Guidelines
UR - http://www.scopus.com/inward/record.url?scp=33645053537&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33645053537&partnerID=8YFLogxK
U2 - 10.6004/jnccn.2006.0004
DO - 10.6004/jnccn.2006.0004
M3 - Review article
C2 - 16403402
AN - SCOPUS:33645053537
SN - 1540-1405
VL - 4
SP - 16
EP - 36
JO - Journal of the National Comprehensive Cancer Network : JNCCN
JF - Journal of the National Comprehensive Cancer Network : JNCCN
IS - 1
ER -