Acute biochemical responses to moderate beer drinking

G. V. Gill, P. H. Baylis, C. T G Flear, A. W. Skillen, P. H. Diggle

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


The consequences of drinking 6 pints of beer (3.3 l) over 3 hours were investigated in 6 healthy men. The expected rise in plasma osmolality, fall in plasma vasopressin concentration, and increase in free water clearance occurred; these variables had returned to normal by 9 hours. There was a small but significant fall in plasma concentrations of urea and creatinine accompanied by a rise in plasma potassium concentration. Serum activities of alkaline phosphatase, gamma-glutamyl transferase, creatinine kinase, and lactate dehydrogenase did not change, and there was no alcohol-induced hypoglycaemia. All subjects had a slight hangover, but none was fluid depleted. It is concluded that, apart from inducing changes in water balance, alcohol in this form causes remarkably little metabolic disturbance.

Original languageEnglish (US)
Pages (from-to)1770-1773
Number of pages4
JournalBMJ (Online)
Issue number6357
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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