Active enhancement of dog kidney allografts using ALG and donor platelets

W. Rowinski; T. Ryffa; S. Stepkowski; B. Woźniewicz; M. Ruka; B. Wasowska; M. Hay; W. Olszewski

Active enhancement of dog kidney allografts using ALG and donor platelets

W. Rowinski, T. Ryffa, S. Stepkowski, B. Woźniewicz, M. Ruka, B. Wasowska, M. Hay, W. Olszewski

Research output: Contribution to journal › Article › peer-review

Abstract

The results of the studies indicate that platelets can be used as donor specific antigen in protocols of 'biological suppression'. Administration of donor specific platelets 10 days after transplantation to unmatched mongrel dogs treated for a brief period with ALG resulted in a marked prolongation of kidney allograft survival. Acute rejection of a second kidney from an indifferent donor suggests that a state of specific unresponsiveness was achieved by recipient pretreatment with ALG and donor antigen challenge.

Original language	English (US)
Pages (from-to)	1013-1019
Number of pages	7
Journal	Archivum Immunologiae et Therapiae Experimentalis
Volume	26
Issue number	1-6
State	Published - 1979
Externally published	Yes

ASJC Scopus subject areas

Immunology

Cite this

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title = "Active enhancement of dog kidney allografts using ALG and donor platelets",

abstract = "The results of the studies indicate that platelets can be used as donor specific antigen in protocols of 'biological suppression'. Administration of donor specific platelets 10 days after transplantation to unmatched mongrel dogs treated for a brief period with ALG resulted in a marked prolongation of kidney allograft survival. Acute rejection of a second kidney from an indifferent donor suggests that a state of specific unresponsiveness was achieved by recipient pretreatment with ALG and donor antigen challenge.",

author = "W. Rowinski and T. Ryffa and S. Stepkowski and B. Wo{\'z}niewicz and M. Ruka and B. Wasowska and M. Hay and W. Olszewski",

year = "1979",

language = "English (US)",

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T1 - Active enhancement of dog kidney allografts using ALG and donor platelets

AU - Rowinski, W.

AU - Ryffa, T.

AU - Stepkowski, S.

AU - Woźniewicz, B.

AU - Ruka, M.

AU - Wasowska, B.

AU - Hay, M.

AU - Olszewski, W.

PY - 1979

Y1 - 1979

N2 - The results of the studies indicate that platelets can be used as donor specific antigen in protocols of 'biological suppression'. Administration of donor specific platelets 10 days after transplantation to unmatched mongrel dogs treated for a brief period with ALG resulted in a marked prolongation of kidney allograft survival. Acute rejection of a second kidney from an indifferent donor suggests that a state of specific unresponsiveness was achieved by recipient pretreatment with ALG and donor antigen challenge.

AB - The results of the studies indicate that platelets can be used as donor specific antigen in protocols of 'biological suppression'. Administration of donor specific platelets 10 days after transplantation to unmatched mongrel dogs treated for a brief period with ALG resulted in a marked prolongation of kidney allograft survival. Acute rejection of a second kidney from an indifferent donor suggests that a state of specific unresponsiveness was achieved by recipient pretreatment with ALG and donor antigen challenge.

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AN - SCOPUS:0018403254

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JO - Archivum Immunologiae et Therapiae Experimentalis

JF - Archivum Immunologiae et Therapiae Experimentalis

IS - 1-6

ER -

Active enhancement of dog kidney allografts using ALG and donor platelets

Abstract

ASJC Scopus subject areas

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